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Insoon Chang Selected Research

Neoplasms (Cancer)

1/2024Targeting of lysosomal-bound protein mEAK-7 for cancer therapy.
1/2021Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress.
1/2017Targeting BMI1+ Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma.
1/2016Inhibition of HDAC6 Protein Enhances Bortezomib-induced Apoptosis in Head and Neck Squamous Cell Carcinoma (HNSCC) by Reducing Autophagy.
7/2010PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells.

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Insoon Chang Research Topics

Disease

5Neoplasms (Cancer)
01/2024 - 07/2010
5Squamous Cell Carcinoma of Head and Neck
01/2017 - 07/2010
2Neoplasm Metastasis (Metastasis)
01/2021 - 01/2017
1Infections
10/2023
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2021
1Bites and Stings (Sting)
01/2021
1Lymphatic Metastasis
01/2017

Drug/Important Bio-Agent (IBA)

2Proteins (Proteins, Gene)FDA Link
01/2024 - 01/2016
2Cisplatin (Platino)FDA LinkGeneric
01/2017 - 01/2016
2trichostatin A (A 300)IBA
01/2016 - 07/2010
2Bortezomib (Velcade)FDA Link
01/2016 - 07/2010
2Histone Deacetylase InhibitorsIBA
01/2016 - 07/2010
2Proteasome InhibitorsIBA
01/2016 - 07/2010
1Lysosomal Membrane ProteinsIBA
01/2024
1Sirolimus (Rapamycin)FDA Link
01/2024
1ChemokinesIBA
10/2023
1CytokinesIBA
10/2023
1Histones (Histone)IBA
01/2021
1Lysine (L-Lysine)FDA Link
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1HeterochromatinIBA
01/2021
1Group IV Phospholipases A2IBA
01/2017
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2017
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2017
1Histone Deacetylase 6IBA
01/2016
1TOR Serine-Threonine KinasesIBA
01/2016
1beta CateninIBA
07/2010
1CaspasesIBA
07/2010
1theasinensin AIBA
07/2010
1Histone Deacetylases (Histone Deacetylase)IBA
07/2010

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2017 - 01/2016
1Therapeutics
01/2024
1Immunotherapy
01/2021